SUNDAY, 9 June

14:00-19:00 Hotel check-in; registration in ground floor atrium; poster board set up; exhibitor set up
19.00-20:00 Honoree Presentation, Professor Thomas Wight
20:00-22:00 Welcome Reception

MONDAY, 10 June

07:00-08:00 Coffee and biscuits in hotel atrium
08:00-08:50 Keynote Speaker: Professor Anthony Day
Understanding HA-protein interactions: state of play and future perspectives
08:50-10:30 Session 1: Chronic disease 1 HA in cardiovascular and pulmonary disease
Chairs: Paul Noble and Manuela Viola
08:50-09:10 Paul Noble: Hyaluronan in lung disease
09:10-09:30 Manuela Viola: Alterations in hyaluronan metabolism in vascular cells
09:30-10:30 Selected abstract talks and flash poster presentations
10:30-11:00 Break
11:00-13:00 Session 2: HA in Stem Cells, Growth & Differentiation
Chairs: Tony Day and Naoki Itano
11:00-11:20 Naoki Itano: Enhanced hexosamine metabolism drives a metabolic and signaling circuit involving hyaluronan production and O-GlcNAcylation to promote cancer stem-like properties.
11:20-13:00 Selected abstract talks and flash poster presentations
13:00-14:00 Lunch
14:00-15:30 Poster Session 1
15:30-16:00 Break
16:00-18:00 Session 3: HA Physics, Chemistry and Structure
Chairs: Mary Cowman and Ralph Richter
16:00-16:20 Mary Cowman: HA content, size, modification and interactions. One molecule, many roles.
16:20-16:40 Ralph Richter: Hyaluronan and its cell-surface receptors - how mechanical factors regulate cell-matrix communication
16:40-18:00 Selected abstract talks and flash poster presentations

TUESDAY, 11 June

07:00-08:00 Coffee and biscuits in hotel atrium
08:00-08:50 Keynote Speaker: Laura Nagy, HA and Liver Disease
HA35: Interruption of the gut:liver inflammatory cycle in alcohol-related liver disease
08:50-10:30 Session 4: Chronic Disease 2 HA in renal, diabetes and joint disease
Chairs: Anna Plaas and Soma Meran
08:50-09:10 Anna Plaas: Therapeutic hyaluronan in musculoskeletal disease: New insights into tissue and cell-specific targets.
09:10-09:30 Soma Meran: Do HAS isoenzymes regulate distinct subsets of myofibroblasts in chronic kidney disease?
09:30-10:30 Selected abstract talks and flash poster presentations
10:30-11:00 Break
11:00-13:00 Session 5:HA Metabolism and Assembly
Chairs: Paul DeAngelis and Davide Vigetti
11:00-11:20 Paul DeAngelis: Current thoughts on structure/function of HA synthesis and degradation enzymes.
11:20-11:40 Davide Vigetti: HAS2-AS1 more than a HAS2 regulator
11:40-13:00 Selected abstract talks and flash poster presentations
13:00-14:00 Lunch
14:00-15:30 Poster Session 2
15:30-16:00 Break
16:00-18:00 Session 6: HA Signalling
Chair: Eva Turley and Cheryl Knudson
16:00-16:20 Eva Turley: The role of hyaluronan in microenvironmental selection of mutant genotypes
16:20-16:40 Cheryl Knudson: The role of HA endocytosis in modulation of cell phenotype
16:40-18:00 Selected abstract talks and flash poster presentations

WEDNESDAY, 12 June

07:00-08:00 Coffee and biscuits in hotel atrium
08:00-10:00 Session 7: Novel HA Interactions in Biology and Disease
Chairs: Yu Yamaguchi and Ellen Puré
08:00-08:20 Yu Yamaguchi : TMEM2: Its physiological significance as the key hyaluronidase that functions on the cell surface
08:20-08:40 Ellen Puré: Dichotomy of impact of CD44 expressed on neoplastic and non-neoplastic cells in a mouse model of pancreatic cancer
08:40-10:00 Selected abstract talks and flash poster presentations
10:00-10:30 Break
10:30-12:30 Session 8: HA in Immunity and Inflammation
Chairs: Carol De La Motte and Michelle Pritchard
10:30-10:50 Carol De La Motte: A role for platelet hyaluronidase-2 in modulating intestinal inflammation
10:50-11:10 Michele Pritchard: Hyaluronan synthesis is required for liver regeneration after acute injury
11:10-12:30 Selected abstract talks and flash poster presentations
12:30-13:30 Lunch
13:30-14:15 ISHAS Business Meeting
13:30-15:30 Poster Session 3
18:00 Banquet at Caldicot Castle
Coaches will leave from the Cardiff Hilton at 18.00

THURSDAY, 13 June

07:00-08:00 Coffee and biscuits in hotel atrium
08:00-08:50 Keynote Speaker: Cathy Merry
The current state and future of Glycomics research
08:50-10:30 Session 9: HA in Cancer Biology
Chairs: Melanie Simpson and David Jackson
08:50-09:10 Melanie Simpson: Nucleotide sugar partitioning deregulates androgen dependence in prostate tumor cells.
09:10-09:30 David Jackson: The emerging role of hyaluronan and its receptors for cell trafficking in the lymphatics.
09:30-10:30 Selected abstract talks and flash poster presentations
10:30-11:00 Break
11:00-13:00 Session 10: HA in Development and Ageing
Chairs: Robert Steadman and Bruno Flamion
11:00-11:20 Robert Steadman: Does HA control the loss of response in chronic wounds.
11:20-11:40 Bruno Flamion: Hyaluronan and ageing.
11:40-13:00 Selected abstract talks
13:00-14:00 Close of Meeting and Lunch

Organisers and the Scientific Committee prohibit photography at all the scientific sessions, including the poster sessions, without the express consent of the author.

Presenters should be at their posters to discuss their research during the poster sessions on Monday, Tuesday and Wednesday.

HA 2019 Platinum Sponsors

HTL
Matrix Bio
Halozyme

HA 2019 Gold Sponsors

LIfecore
Bloomage

HA 2019 Silver Sponsors

Mizutani
Mizutani

HA 2019 Bronze Sponsors

Hyalose
TissueTech
EBI-Echelon

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